Knee Osteoarthritis — From Injections to Robotic Replacement
Worn knee cartilage causing pain, swelling, and stiffness. Stryker Mako robotic knee replacement achieves sub-millimetre precision for lasting relief.

Knee Osteoarthritis
Knee osteoarthritis is progressive loss of articular cartilage leading to pain, swelling, deformity, and disability. It is the most common joint disease worldwide and the leading indication for knee replacement.
Conservative measures — weight loss, physiotherapy, injections — delay surgery for many patients. When quality of life is sufficiently impaired, Stryker Mako robotic-assisted TKA delivers highly accurate, personalised implant positioning.
- Affects 10% of adults over 55; significantly more over 65
- Medial compartment is most commonly affected (varus deformity)
- X-ray shows joint space narrowing, osteophytes, and subchondral sclerosis
- Mako robotic TKA reduces outliers in alignment by 70% vs conventional
Surgical Results at Central Hospital

Central Hospital Istanbul

Central Hospital Istanbul
Step-by-Step Knee Arthritis Management
Conservative Management
Weight loss, low-impact exercise, knee brace, NSAIDs, and activity modification form the first-line management.
Intra-articular Injections
Corticosteroid (rapid relief), hyaluronic acid (3–6 months), or PRP (biological stimulation) — guided by ultrasound.
Partial Knee Replacement (UKA)
Unicompartmental knee arthroplasty for isolated medial or lateral compartment arthritis — preserves cruciate ligaments, faster recovery.
Total Knee Replacement — Stryker Mako
Robotic arm-assisted TKA with CT-based 3D planning. Implant placed within 1 mm of plan — optimal kinematics and longevity.
World-class orthopaedic care at a fraction of Western costs
50–70% Cost Saving
JCI-accredited surgery at 30–50% of UK / US prices — without compromising implant quality or surgical standards.
Fast Access
Consultations within 48 hours. Surgery typically scheduled within 1–2 weeks, versus months of waiting in public systems.
26 Specialists
A multidisciplinary team of orthopedic surgeons, spine surgeons, PM&R physicians and physiotherapists under one roof.
47 Countries
We coordinate everything — airport transfers, hotel, interpreter, medical visa letter — so you focus only on recovery.
From first contact to full recovery — we handle every step
Online Consultation
Share MRI/X-ray scans and medical history. Our team reviews and responds within 24 hours with a personalised treatment plan and cost estimate.
Travel & Admission
We arrange airport transfer, hotel recommendations, and hospital admission. A dedicated patient coordinator is available throughout.
Surgery & Hospital Stay
Procedure performed by your assigned surgeon. Private room, daily physiotherapy, and nursing care included in the package.
Recovery & Rehabilitation
Robotic physiotherapy and supervised exercise begin early. Discharge criteria are met before your return flight is booked.
Remote Follow-up
Video consultations at 6 weeks, 3 months, and 1 year. Your home physician receives a full surgical report.
Get a consultation for this condition
Ready to take the first step?
Send your MRI or X-rays today. Our team reviews every case within 24 hours — no obligation, no cost.
- Surgeon reviews your scans and sends a written opinion within 24 h
- You receive a full cost estimate with no hidden fees
- We arrange travel, hotel and hospital — you focus on getting better